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A grant from HHS-NIH11

NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed)

This Parent R01 opportunity is potentially suitable for a discrete, specified, circumscribed research project that relates to the scientific mission of one or more participating NIH Institutes or Centers and does not propose a clinical trial. Many domestic, tribal, governmental, nonprofit, academic, business, and other listed entity types may be eligible, but an individual applicant’s status must be verified. The supplied packet does not provide award amounts, duration, formal review criteria, or the full application instructions; applicants should consult PA-25-301 and confirm submission requirements before proceeding.

Start here · Eligibility

Check whether your organization qualifies

Answer 5 focused questions in about 60 seconds before investing time in the application.

Take Eligibility Quiz
2 source-confirmed criteria · No signupReview criteria

Potential award

Not specified

Time remaining

502 days

Application load

Moderate effort

Best next move

Take the eligibility quiz

Apply

Verified against the source on 8/22/2026

01

Start here

Confirm eligibility

Check your fit in about 60 seconds.

Eligibility requirementsQuestion 1 of 5
About 60 seconds totalConfirmed criterion

Does your organization have the required nonprofit status?

What does this mean?

Eligible nonprofits are named in the source requirements.

Review supporting source ↗
Does your organization have the required nonprofit status?
Select an answer to continue

No signup · Answers stay in this browser session

This is an explainable self-assessment, not a win probability or legal determination. Hard eligibility conflicts are never averaged against softer program-fit signals. Always verify the official notice.

Optional Review source criteria and citations

Nonprofit status

Eligible nonprofits are named in the source requirements.

Review source ↗
confirmed

Geography

Nationwide availability is inferred from the catalog record; confirm the official notice.

Review source ↗
inferred

Organization size

No organization-size limit was captured.

Review source ↗
unclear

Program area

Education, Environment, Food and Nutrition, Health, Income Security and Social Services, Human Services, Research

Review source ↗
inferred

Population served

No specific population was captured.

Review source ↗
unclear

Matching funds

No cost share is indicated.

Review source ↗
confirmed

Registrations

SAM.gov and Grants.gov registration may be required; confirm in the notice.

Review source ↗
inferred

Exclusions

Review the full notice for exclusions and prohibited uses.

Review source ↗
unclear
02

Grant-writer assessment

Understand the opportunity

Start with the practical interpretation. Open the complete source narrative when you need the underlying detail.

Plain-English explanation

Plain-English explanation

This Parent R01 opportunity is potentially suitable for a discrete, specified, circumscribed research project that relates to the scientific mission of one or more participating NIH Institutes or Centers and does not propose a clinical trial. Many domestic, tribal, governmental, nonprofit, academic, business, and other listed entity types may be eligible, but an individual applicant’s status must be verified. The supplied packet does not provide award amounts, duration, formal review criteria, or the full application instructions; applicants should consult PA-25-301 and confirm submission requirements before proceeding.

Editorial analysis

What the funder is trying to accomplish

NIH supports discrete, specified, circumscribed research projects in areas representing the interests and competencies of the investigator(s), provided the project relates to the programmatic interests and scientific missions of one or more participating NIH Institutes and Centers. Applications proposing clinical trial(s) are not accepted.

Editorial analysis

Strong-fit project signals

The work is a discrete, specified, circumscribed research project. The project can be tied directly to the programmatic interests and scientific mission of one or more participating NIH Institutes or Centers. The project does not propose a clinical trial. The applicant is within a listed eligible category, subject to confirmation of its precise legal and organizational status.

Editorial analysis

What reviewers may prioritize

The supplied packet does not state formal review criteria or scoring priorities. It is reasonably inferred that reviewers or program staff will need to determine whether the project is a bounded research effort, relates to a participating NIH Institute or Center’s scientific mission, and avoids proposing a clinical trial, because these are express program conditions.

Source dossier Read the full official program description
Source-backed synopsis

What this grant funds

The NIH Research Project Grant supports a discrete, specified, circumscribed project in areas representing the specific interests and competencies of the investigator(s). The proposed project must be related to the programmatic interests of one or more of the participating NIH Institutes and Centers (ICs) based on their scientific missions.This Notice of Funding Opportunity does not accept applications proposing clinical trial(s).

Read the complete official description ↗
03

Decision economics

Size the opportunity

Use the source facts below to judge whether the likely return justifies the application effort.

Award range
Not specified
Total program funding
Not specified
Expected awards
Not specified
Geography
National
Cost share
Not indicated
Assistance listing
Not specified

Mission alignment

Compare your program with Education, Environment, Food and Nutrition.

Geographic fit

National

04

Working plan

Build the application

The generated milestones are planning aids. Only the official notice establishes required dates.

Requirements captured

Other requirements
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.
Submission system
Grants.gov
Attachments
https://grants.nih.gov/grants/guide/pa-files/PA-25-301.html, PA-25-301 Full Announcement Text
Contact
National Institutes of Health · grantsinfo@nih.gov · 301-402-2541

Official deadline

January 7, 2028

Moderate effort based on requirements currently captured.

  1. Confirm eligibility, registrations, partners, and internal approval.

  2. Finalize project design, outcomes, and supporting evidence.

  3. Draft the narrative and detailed budget.

  4. Complete compliance review and collect attachments.

  5. Submit early and preserve the confirmation receipt.

05Past behaviorCompare historical awardsHistorical patterns provide context, but do not predict or guarantee future funding decisions.
No licensed historical awards are currently linked to this opportunity.
06Audit trailVerify the evidenceSee where the facts came from, when they were checked, and what has materially changed.

Source record

Source verified means the official record was successfully checked. It does not mean every eligibility or application field has been extracted.

Verification
verified
Source
grants gov
Last checked
8/22/2026, 8:50:48 AM
Content updated
8/22/2026, 8:50:51 AM
Review
Automated normalization; not yet expert-reviewed
Open official source ↗

Material changes

  1. Updated eligibility, eligibility details.

  2. Updated eligibility, eligibility details.

  3. Updated eligibility, eligibility details.

  4. Updated eligibility, eligibility details.

  5. Updated eligibility, eligibility details.

  6. Updated eligibility, eligibility details.

  7. Updated eligibility, eligibility details.

  8. Updated eligibility, eligibility details.

  9. Updated eligibility, eligibility details.

  10. Updated eligibility, eligibility details.

  11. Updated eligibility, eligibility details.

  12. Updated eligibility, eligibility details.

Verify before applying. Official funder documents control. Derived analysis and preparation dates should not replace the notice.
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Quick answersFrequently asked questionsGet concise answers about NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed).
Is NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed) currently open?

Yes, based on the latest source record. The deadline is January 7, 2028, with 502 days remaining. Because funders can amend or extend notices, confirm the date and submission instructions on the official application page. The source was last checked 8/22/2026.

How much funding does NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed) provide?

NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed) lists Not specified per award. The expected number of awards has not been captured, so the award range alone should not be treated as an estimate of competitiveness.

Who can apply to NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed)?

For profit organizations other than small businesses; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Private institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); State governments;… Applicants should still complete the eligibility quiz and verify every condition in the official notice; a general fit does not override exclusions or registration requirements.

Does NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed) require matching funds?

No cost-share requirement is indicated in the captured source facts. Applicants should still verify the official budget instructions in case an amendment, program track, or specific cost category carries additional conditions.

What should I prepare before applying to NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed)?

Moderate effort is expected. The captured requirements include other requirements, submission system, attachments, contact. Start by confirming eligibility and registrations, then work backward from January 7, 2028 using the preparation plan above.

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