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A grant from HHS-NIH11

Single Source for Continuation of the Integrated Islet Distribution Program U24 (Clinical Trial Not Allowed) Grant

This is a highly restricted NIH/NIDDK single-source continuation opportunity for the Integrated Islet Distribution Program (IIDP). The notice identifies Beckman Research Institute/City of Hope and only PI/PDs associated with the award issued under RFA-DK-20-509 as eligible. One award is expected; the listed award ceiling is $2.2 million, with $3.3 million in total listed funding. The continuation is intended to maintain IIDP’s mission of working with qualified islet-isolation facilities to prepare and distribute human islets for biomedical diabetes research. Organizations or PI/PD teams outside the specified incumbent relationship should not invest in an application unless the full NOFO establishes an applicable exception or clarification.

Start here · Eligibility

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1 source-confirmed criterion · No signupReview criteria

Potential award

Up to $2,200,000

Time remaining

38 days

Application load

Moderate effort

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Verified against the source on 8/22/2026

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Confirm eligibility

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Eligibility requirementsQuestion 1 of 5

About 60 seconds totalInferred criterion

Does your proposed work directly align with Health, Human Services, Community Development, Equipment, Research?

What does this mean?

Health, Human Services, Community Development, Equipment, Research

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This is an explainable self-assessment, not a win probability or legal determination. Hard eligibility conflicts are never averaged against softer program-fit signals. Always verify the official notice.

Optional Review source criteria and citations

Nonprofit status

Confirm nonprofit eligibility in the full notice.

Review source ↗

unclear

Geography

Nationwide availability is inferred from the catalog record; confirm the official notice.

Review source ↗

inferred

Organization size

No organization-size limit was captured.

Review source ↗

unclear

Program area

Health, Human Services, Community Development, Equipment, Research

Review source ↗

inferred

Population served

No specific population was captured.

Review source ↗

unclear

Matching funds

No cost share is indicated.

Review source ↗

confirmed

Registrations

SAM.gov and Grants.gov registration may be required; confirm in the notice.

Review source ↗

inferred

Exclusions

Review the full notice for exclusions and prohibited uses.

Review source ↗

unclear

Grant-writer assessment

Understand the opportunity

Start with the practical interpretation. Open the complete source narrative when you need the underlying detail.

Plain-English explanation

Editorial analysis

What the funder is trying to accomplish

NIDDK intends to renew the current IIDP through a single-source cooperative agreement and maintain its continuing mission to provide human-islet resources for diabetes research. IIDP does this by partnering with qualified islet-isolation facilities to prepare and distribute human islets to biomedical researchers. The notice also states that the NOFO is associated with the Special Diabetes Program.

Editorial analysis

Strong-fit project signals

The proposed PI/PDs are associated with the award issued under RFA-DK-20-509 to Beckman Research Institute/City of Hope. The proposal continues IIDP’s stated model of partnerships with qualified islet-isolation facilities that prepare and distribute human islets to biomedical researchers. The proposed work preserves the resource-distribution mission identified in the notice: supporting diabetes research, including work to advance understanding of human islet cell biology and development of diabetes prevention and treatment therapies. The applicant has current SAM.gov and Grants.gov registrations and can submit through Grants.gov.

Editorial analysis

What reviewers may prioritize

The packet does not provide formal NIH review criteria or scoring weights. The most supportable inferred priorities are continuity of IIDP’s stated mission, a credible plan for partnerships with qualified islet-isolation facilities, continued preparation and distribution of human islets to biomedical researchers, and relevance of the resource to diabetes research. These are program-purpose inferences, not confirmed review criteria.

Source dossier Read the full official program description

Source-backed synopsis

What this grant funds

This is a NOFO for a Single Source competition that will invite application(s) from eligible organization(s) to apply. Please see Eligibility Section for additional information. In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) will be considered for funding.The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) is announcing its intent to issue a single source cooperative agreement award to Beckman Research Institute/City of Hope for the currently funded Integrated Islet Distribution Program (IIDP) to renew the program and maintain support for its continuing mission to provide the scientific community with important islet resources for diabetes research. The IIDP facilitates the distribution of human islets to biomedical researchers by establishing partnerships with qualified islet isolation facilities to prepare and distribute human islets. Human islets remain an essential resource for diabetes research to advance our understanding of human islet cell biology, and to promote the development of new therapies for the prevention and treatment of diabetes.This NOFO is associated with the Special Diabetes Program (https://www.niddk.nih.gov/about-niddk/research-areas/diabetes/type-1-diabetes-special-statutory-funding-program/about-special-diabetes-program) which funds research on the prevention, treatment, and cure of type 1 diabetes and its complications, including unique, innovative, and collaborative research consortia and clinical trials networks.

Read the complete official description ↗

Decision economics

Size the opportunity

Use the source facts below to judge whether the likely return justifies the application effort.

Award range: Up to $2,200,000
Total program funding: $3,300,000
Expected awards: 1
Geography: National
Cost share: Not indicated
Assistance listing: Not specified

Mission alignment

Compare your program with Health, Human Services, Community Development.

Geographic fit

National

Working plan

Build the application

The generated milestones are planning aids. Only the official notice establishes required dates.

Requirements captured

Other requirements: Only the PI/PDs associated with the award issued under RFA-DK-20-509 to Beckman Research Institute/City of Hope is eligible to apply for this single source funding. Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/Foreign Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
Submission system: Grants.gov
Attachments: RFA-DK-27-147-Full-Announcement.html
Contact: National Institutes of Health · NIDDK_DEM@nih.gov · 301-402-2541

Official deadline

September 30, 2026

Moderate effort based on requirements currently captured.

August 31, 2026
Confirm eligibility, registrations, partners, and internal approval.
September 9, 2026
Finalize project design, outcomes, and supporting evidence.
September 16, 2026
Draft the narrative and detailed budget.
September 23, 2026
Complete compliance review and collect attachments.
September 28, 2026
Submit early and preserve the confirmation receipt.

05Past behaviorCompare historical awardsHistorical patterns provide context, but do not predict or guarantee future funding decisions.

No licensed historical awards are currently linked to this opportunity.

06Audit trailVerify the evidenceSee where the facts came from, when they were checked, and what has materially changed.

Source record

Source verified means the official record was successfully checked. It does not mean every eligibility or application field has been extracted.

Verification: verified
Source: grants gov
Last checked: 8/22/2026, 8:50:56 AM
Content updated: 8/12/2026, 1:44:57 AM
Review: Automated normalization; not yet expert-reviewed

Open official source ↗

Material changes

8/11/2026
Updated categories.
8/10/2026
Updated categories.
8/10/2026
Updated categories.
8/7/2026
Updated amount max, application details, categories, cost share required, deadline, description, eligibility, eligibility details, expected awards, important dates, name, requirements, source citations, status, total funding.
8/6/2026
Updated tracking started.

Verify before applying. Official funder documents control. Derived analysis and preparation dates should not replace the notice.

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Quick answersFrequently asked questionsGet concise answers about Single Source for Continuation of the Integrated Islet Distribution Program U24 (Clinical Trial Not Allowed) Grant.

Is Single Source for Continuation of the Integrated Islet Distribution Program U24 (Clinical Trial Not Allowed) Grant currently open?

Yes, based on the latest source record. The deadline is September 30, 2026, with 38 days remaining. Because funders can amend or extend notices, confirm the date and submission instructions on the official application page. The source was last checked 8/22/2026.

How much funding does Single Source for Continuation of the Integrated Islet Distribution Program U24 (Clinical Trial Not Allowed) Grant provide?

Single Source for Continuation of the Integrated Islet Distribution Program U24 (Clinical Trial Not Allowed) Grant lists Up to $2,200,000 per award. The total program funding recorded is $3,300,000. HHS-NIH11 expects to make approximately 1 award, although the final number may vary.

Who can apply to Single Source for Continuation of the Integrated Islet Distribution Program U24 (Clinical Trial Not Allowed) Grant?

Others (see text field entitled "Additional Information on Eligibility" for clarification) Applicants should still complete the eligibility quiz and verify every condition in the official notice; a general fit does not override exclusions or registration requirements.

Does Single Source for Continuation of the Integrated Islet Distribution Program U24 (Clinical Trial Not Allowed) Grant require matching funds?

No cost-share requirement is indicated in the captured source facts. Applicants should still verify the official budget instructions in case an amendment, program track, or specific cost category carries additional conditions.

What should I prepare before applying to Single Source for Continuation of the Integrated Islet Distribution Program U24 (Clinical Trial Not Allowed) Grant?

Moderate effort is expected. The captured requirements include other requirements, submission system, attachments, contact. Start by confirming eligibility and registrations, then work backward from September 30, 2026 using the preparation plan above.