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A grant from NSF

Division of Integrative Organismal Systems Core Programs (IOS) Grant

NSF’s IOS Core Programs Track supports organism-centered biological research across listed IOS areas, with encouragement for systems approaches that yield conceptual or theoretical insight and predictions about emergent organismal properties. The IntBIO Track specifically invites collaborative proposals addressing bold questions through synergistic integration across subdisciplines and, where relevant, biological scales. Eligible submitters are specified U.S.-located nonprofit research-related organizations and accredited U.S. two- and four-year IHEs acting for faculty. Applicants should confirm the active notice, deadline, award parameters, and any track-specific instructions before planning.

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1 source-confirmed criterion · No signupReview criteria

Potential award

Not specified

Time remaining

Rolling or unknown

Application load

Moderate effort

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Verified against the source on 8/21/2026

01

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Confirm eligibility

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Eligibility requirementsQuestion 1 of 5
About 60 seconds totalInferred criterion

Does your proposed work directly align with Science and Technology and other Research and Development, Science, Research, Environment?

What does this mean?

Science and Technology and other Research and Development, Science, Research, Environment

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This is an explainable self-assessment, not a win probability or legal determination. Hard eligibility conflicts are never averaged against softer program-fit signals. Always verify the official notice.

Optional Review source criteria and citations

Nonprofit status

Confirm nonprofit eligibility in the full notice.

Review source ↗
unclear

Geography

Nationwide availability is inferred from the catalog record; confirm the official notice.

Review source ↗
inferred

Organization size

No organization-size limit was captured.

Review source ↗
unclear

Program area

Science and Technology and other Research and Development, Science, Research, Environment

Review source ↗
inferred

Population served

No specific population was captured.

Review source ↗
unclear

Matching funds

No cost share is indicated.

Review source ↗
confirmed

Registrations

SAM.gov and Grants.gov registration may be required; confirm in the notice.

Review source ↗
inferred

Exclusions

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Review source ↗
unclear
02

Grant-writer assessment

Understand the opportunity

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Plain-English explanation

Plain-English explanation

NSF’s IOS Core Programs Track supports organism-centered biological research across listed IOS areas, with encouragement for systems approaches that yield conceptual or theoretical insight and predictions about emergent organismal properties. The IntBIO Track specifically invites collaborative proposals addressing bold questions through synergistic integration across subdisciplines and, where relevant, biological scales. Eligible submitters are specified U.S.-located nonprofit research-related organizations and accredited U.S. two- and four-year IHEs acting for faculty. Applicants should confirm the active notice, deadline, award parameters, and any track-specific instructions before planning.

Editorial analysis

What the funder is trying to accomplish

The program supports research explaining why organisms are structured as they are and function as they do. Proposals should focus on organisms as a fundamental unit of biological organization, and PIs are encouraged to use systems approaches that produce conceptual and theoretical insights and predictions about emergent organismal properties. The IntBIO Track invites collaborative proposals on bold questions requiring integrated approaches for substantive progress.

Editorial analysis

Strong-fit project signals

The research focuses on organisms as a fundamental unit of biological organization. The project addresses a named area of inquiry, including developmental biology; nervous-system development, structure, modification, function, or evolution; biomechanics and functional morphology; physiology; symbioses and microbial interactions; organism–environment interactions; plant and animal genomics; or animal behavior. The research uses systems approaches intended to produce conceptual or theoretical insights and predictions about emergent organismal properties. For IntBIO, a collaborative project tackles a bold biological question through integrated work across subdisciplines, methods, tools, or concepts, with a synergistic outcome. Where appropriate to the question, the project connects scales of organization and uses experimental strategies, modeling, integrative analysis, advanced computation, or other approaches to stimulate discovery and general theory.

Editorial analysis

What reviewers may prioritize

The packet supplies no formal review criteria or reviewer-priority language. As an inference from the program description, applicants should make explicit the organism-centered problem, the logic connecting disciplines or approaches, and the intended conceptual, theoretical, predictive, or—where applicable—cross-scale advance. This is preparation guidance, not a stated scoring criterion.

Source dossier Read the full official program description
Source-backed synopsis

What this grant funds

The Division of Integrative Organismal Systems (IOS) Core Programs Track supports research to understand why organisms are structured the way they are and function as they do. Proposals are welcomed in all of the core scientific program areas supported by the Division of Integrative Organismal Systems (IOS). Areas of inquiry include, but are not limited to, developmental biology and the evolution of developmental processes, development, structure, modification, function, and evolution of the nervous system, biomechanics and functional morphology, physiological processes, symbioses and microbial interactions, interactions of organisms with biotic and abiotic environments, plant and animal genomics, and animal behavior. Proposals should focus on organisms as a fundamental unit of biological organization. Principal Investigators are encouraged to apply systems approaches that will lead to conceptual and theoretical insights and predictions about emergent organismal properties.

The IntBIO Track invites submission of collaborative proposals to tackle bold questions in biology that require an integrated approach to make substantive progress. Integrative biological research spans subdisciplines and incorporates cutting-edge methods, tools, and concepts from each to produce groundbreaking biological discovery that is synergistic, such that the whole is greater than the sum of the parts. The research should produce a novel, holistic understanding of how biological systems function and interact across different scales of organization, e.g., from molecules to cells, tissues to organisms, species to ecosystems and the entire Earth. Where appropriate, projects should apply experimental strategies, modeling, integrative analysis, advanced computation, or other research approaches to stimulate new discovery and general theory in biology.

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03

Decision economics

Size the opportunity

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Award range
Not specified
Total program funding
$70,000,000
Expected awards
Not specified
Geography
National
Cost share
Not indicated
Assistance listing
Not specified

Mission alignment

Compare your program with Science and Technology and other Research and Development, Science, Research.

Geographic fit

National

04

Working plan

Build the application

The generated milestones are planning aids. Only the official notice establishes required dates.

Requirements captured

Other requirements
*Who May Submit Proposals: Proposals may only be submitted by the following: -Non-profit, non-academic organizations: Independent museums, observatories, research laboratories, professional societies and similar organizations located in the U.S. that are directly associated with educational or research activities. -Institutions of Higher Education (IHEs): Two- and four-year IHEs (including community colleges) accredited in, and having a campus located in the US, acting on behalf of their faculty members. Special Instructions for International Branch Campuses of US IHEs: If the proposal includes funding to be provided to an international branch campus of a US institution of higher education (including through use of sub-awards and consultant arrangements), the proposer must explain the benefit(s) to the project of performance at the international branch campus, and justify why the project activities cannot be performed at the US campus.
Submission system
Grants.gov
Attachments
NSF Publication 24-546
Contact
U.S. National Science Foundation · grantsgovsupport@nsf.gov · 703-292-4203

Official deadline

Not specified

Moderate effort based on requirements currently captured.

A preparation schedule will appear when a confirmed future deadline is available.

05Past behaviorCompare historical awardsHistorical patterns provide context, but do not predict or guarantee future funding decisions.
No licensed historical awards are currently linked to this opportunity.
06Audit trailVerify the evidenceSee where the facts came from, when they were checked, and what has materially changed.

Source record

Source verified means the official record was successfully checked. It does not mean every eligibility or application field has been extracted.

Verification
verified
Source
grants gov
Last checked
8/21/2026, 9:02:01 AM
Content updated
8/21/2026, 9:02:01 AM
Review
Automated normalization; not yet expert-reviewed
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Material changes

  1. Updated deadline, description, important dates, requirements.

  2. Updated deadline, description, important dates, name.

  3. Updated categories.

  4. Updated categories.

  5. Updated application details, categories, cost share required, description, eligibility, eligibility details, important dates, requirements, source citations, total funding.

  6. Updated tracking started.

Verify before applying. Official funder documents control. Derived analysis and preparation dates should not replace the notice.
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Quick answersFrequently asked questionsGet concise answers about Division of Integrative Organismal Systems Core Programs (IOS) Grant.
Is Division of Integrative Organismal Systems Core Programs (IOS) Grant currently open?

Yes, based on the latest source record. The deadline is Not specified. Because funders can amend or extend notices, confirm the date and submission instructions on the official application page. The source was last checked 8/21/2026.

How much funding does Division of Integrative Organismal Systems Core Programs (IOS) Grant provide?

Division of Integrative Organismal Systems Core Programs (IOS) Grant lists Not specified per award. The total program funding recorded is $70,000,000. The expected number of awards has not been captured, so the award range alone should not be treated as an estimate of competitiveness.

Who can apply to Division of Integrative Organismal Systems Core Programs (IOS) Grant?

Others (see text field entitled "Additional Information on Eligibility" for clarification) Applicants should still complete the eligibility quiz and verify every condition in the official notice; a general fit does not override exclusions or registration requirements.

Does Division of Integrative Organismal Systems Core Programs (IOS) Grant require matching funds?

No cost-share requirement is indicated in the captured source facts. Applicants should still verify the official budget instructions in case an amendment, program track, or specific cost category carries additional conditions.

What should I prepare before applying to Division of Integrative Organismal Systems Core Programs (IOS) Grant?

Moderate effort is expected. The captured requirements include other requirements, submission system, attachments, contact. Start by confirming eligibility and registrations, then work backward from Not specified using the preparation plan above.

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