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A grant from NSF

Infrastructure Innovation for Biological Research (Innovation) Grant

NSF’s Infrastructure Innovation for Biological Research program supports eligible U.S. higher-education institutions and qualifying U.S.…

Official application

Award

$300,000–$800,000

Deadline

October 7, 2076

18252 days

Apply at official source Check your eligibility

No signup · Source checked 10/17/2026

Decision snapshot

Potential award

$300,000–$800,000

Official deadline

October 7, 2076

18252 days

Eligibility evidence

1 confirmed criterion

5 checks available

Application load

Moderate effort

01

Start here

Confirm eligibility

Check your fit in about 60 seconds.

Eligibility requirementsQuestion 1 of 5
About 60 seconds totalInferred criterion

Does your proposed work directly align with Science and Technology and other Research and Development, Science, Research, Community Development, Equipment?

What does this mean?

Science and Technology and other Research and Development, Science, Research, Community Development, Equipment

Review supporting source ↗
Does your proposed work directly align with Science and Technology and other Research and Development, Science, Research, Community Development, Equipment?
Select an answer to continue

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This is an explainable self-assessment, not a win probability or legal determination. Hard eligibility conflicts are never averaged against softer program-fit signals. Always verify the official notice.

Optional Review source criteria and citations

Nonprofit status

Confirm nonprofit eligibility in the full notice.

Review source ↗
unclear

Geography

Nationwide availability is inferred from the catalog record; confirm the official notice.

Review source ↗
inferred

Organization size

No organization-size limit was captured.

Review source ↗
unclear

Program area

Science and Technology and other Research and Development, Science, Research, Community Development, Equipment

Review source ↗
inferred

Population served

No specific population was captured.

Review source ↗
unclear

Matching funds

No cost share is indicated.

Review source ↗
confirmed

Registrations

SAM.gov and Grants.gov registration may be required; confirm in the notice.

Review source ↗
inferred

Exclusions

Review the full notice for exclusions and prohibited uses.

Review source ↗
unclear
02

Grant-writer assessment

Understand the opportunity

Start with the practical interpretation. Open the complete source narrative when you need the underlying detail.

Plain-English explanation

Plain-English explanation

NSF’s Infrastructure Innovation for Biological Research program supports eligible U.S. higher-education institutions and qualifying U.S.-located nonprofit, non-academic organizations to develop novel biological research infrastructure, significantly redesign it, or adapt it in novel ways. Projects must fit Bioinformatics, Instrumentation, or Research Methods; address one or more biological science questions; and show potential utility beyond a single research team. Awards are listed at $300,000–$800,000 with no required cost share. The supplied record does not list a deadline or formal review criteria, so applicants should consult NSF Publication 23-578 and the current official notice before preparing or submitting a proposal.

Editorial analysis

What the funder is trying to accomplish

NSF intends to support research that designs novel or greatly improved biological research tools and methods for contemporary biology. The program focuses on broadly applicable infrastructure in Bioinformatics, Instrumentation, and Research Methods that improves researchers’ ability to manipulate, control, analyze, or measure biological systems; advances biological understanding; and can be used by a community beyond one research team.

Editorial analysis

Strong-fit project signals

The work fits Bioinformatics, Instrumentation, or Research Methods, the three programmatic areas named by the program. The project develops novel infrastructure, significantly redesigns existing infrastructure, or adapts existing infrastructure in a novel way. The proposed capability improves the ability to manipulate, control, analyze, or measure critical aspects of biological systems. The proposal identifies one or more biological science questions to which the infrastructure has significant application and explains its anticipated contribution to biological understanding. The infrastructure has potential for use by a community of researchers beyond a single research team.

Editorial analysis

What reviewers may prioritize

The packet does not provide formal review criteria. It is reasonable to infer that reviewers will examine whether the work meets the stated infrastructure threshold, fits a named programmatic area, has significant application to biological science questions, can advance biological understanding, and has potential utility beyond one team. These are program-description-derived fit factors, not confirmed NSF review criteria.

Source dossier Read the full official program description
Source-backed synopsis

What this grant funds

The Infrastructure Innovation for Biological Research Program (Innovation) supports research to design novel or greatly improved research tools and methods that advance contemporary biology in any research area supported by the Directorate for Biological Sciences at NSF. The Innovation Program focuses on research infrastructure that is broadly applicable to researchers in three programmatic areas: Bioinformatics, Instrumentation, and Research Methods. Infrastructure supported by this program is expected to advance biological understanding by improving scientists’ abilities to manipulate, control, analyze, or measure critical aspects of biological systems, which can be essential for addressing important fundamental research questions. Proposals submitted to these programmatic areas can do one of three things to advance or transform research in biology: develop novel infrastructure, significantly redesign existing infrastructure, or adapt existing infrastructure in novel ways. Projects are expected to have a significant application to one or more biological science questions and have the potential to be used by a community of researchers beyond a single research team.

Please refer to the descriptions of individual programmatic areas for detailed guidance on what is supported through this solicitation (see links below).

Read the complete official description ↗
03

Decision economics

Size the opportunity

Use the source facts below to judge whether the likely return justifies the application effort.

Award range
$300,000–$800,000
Total program funding
$18,000,000
Expected awards
40
Geography
National
Cost share
Not indicated
Assistance listing
Not specified

Mission alignment

Compare your program with Science and Technology and other Research and Development, Science, Research.

Geographic fit

National

04

Working plan

Build the application

The generated milestones are planning aids. Only the official notice establishes required dates.

Requirements captured

Other requirements
*Who May Submit Proposals: Proposals may only be submitted by the following: -Non-profit, non-academic organizations: Independent museums, observatories, research laboratories, professional societies and similar organizations located in the U.S. that are directly associated with educational or research activities. -Institutions of Higher Education (IHEs): Two- and four-year IHEs (including community colleges) accredited in, and having a campus located in the US, acting on behalf of their faculty members. Special Instructions for International Branch Campuses of US IHEs: If the proposal includes funding to be provided to an international branch campus of a US institution of higher education (including through use of sub-awards and consultant arrangements), the proposer must explain the benefit(s) to the project of performance at the international branch campus, and justify why the project activities cannot be performed at the US campus. *Who May Serve as PI: There are no restrictions or limits.
Submission system
Grants.gov
Attachments
NSF Publication 23-578
Contact
U.S. National Science Foundation · grantsgovsupport@nsf.gov · 703-292-4203

Official deadline

October 7, 2076

Moderate effort based on requirements currently captured.

  1. Confirm eligibility, registrations, partners, and internal approval.

  2. Finalize project design, outcomes, and supporting evidence.

  3. Draft the narrative and detailed budget.

  4. Complete compliance review and collect attachments.

  5. Submit early and preserve the confirmation receipt.

05Past behaviorCompare historical awardsHistorical patterns provide context, but do not predict or guarantee future funding decisions.
No licensed historical awards are currently linked to this opportunity.
06Audit trailVerify the evidenceSee where the facts came from, when they were checked, and what has materially changed.

Source record

What “source verified” means

The official record was successfully checked. Verification does not mean every eligibility or application field has been extracted. Read the methodology →

Verification
verified
Source
grants gov
Last checked
10/17/2026, 12:14:59 PM
Content updated
10/7/2026, 3:37:57 PM
Review
Automated normalization; not yet expert-reviewed
Open official source ↗

Material changes

  1. Updated deadline, important dates.

  2. Updated deadline, important dates.

  3. Updated deadline, description, important dates, name, requirements.

  4. Updated categories.

  5. Updated categories.

  6. Updated amount max, amount min, application details, categories, cost share required, description, eligibility, eligibility details, expected awards, important dates, requirements, source citations, total funding.

  7. Updated tracking started.

Verify before applying. Official funder documents control. Derived analysis and preparation dates should not replace the notice.
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Quick answersFrequently asked questionsGet concise answers about Infrastructure Innovation for Biological Research (Innovation) Grant.
Is Infrastructure Innovation for Biological Research (Innovation) Grant currently open?

Yes, based on the latest source record. The deadline is October 7, 2076, with 18252 days remaining. Because funders can amend or extend notices, confirm the date and submission instructions on the official application page. The source was last checked 10/17/2026.

How much funding does Infrastructure Innovation for Biological Research (Innovation) Grant provide?

Infrastructure Innovation for Biological Research (Innovation) Grant lists $300,000–$800,000 per award. The total program funding recorded is $18,000,000. NSF expects to make approximately 40 awards, although the final number may vary.

Who can apply to Infrastructure Innovation for Biological Research (Innovation) Grant?

Others (see text field entitled "Additional Information on Eligibility" for clarification) Applicants should still complete the eligibility quiz and verify every condition in the official notice; a general fit does not override exclusions or registration requirements.

Does Infrastructure Innovation for Biological Research (Innovation) Grant require matching funds?

No cost-share requirement is indicated in the captured source facts. Applicants should still verify the official budget instructions in case an amendment, program track, or specific cost category carries additional conditions.

What should I prepare before applying to Infrastructure Innovation for Biological Research (Innovation) Grant?

Moderate effort is expected. The captured requirements include other requirements, submission system, attachments, contact. Start by confirming eligibility and registrations, then work backward from October 7, 2076 using the preparation plan above.