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A grant from HHS-NIH11

Dissemination and Implementation Research in Health (R21 Clinical Trial Optional) Grant

This opportunity supports dissemination and implementation research addressing barriers to the adoption, adaptation, integration, scale-up, and sustainability of evidence-based health interventions and related…

Official application

Award

Not specified

Deadline

January 7, 2028

446 days

Apply at official source Check your eligibility

No signup · Source checked 10/17/2026

Decision snapshot

Potential award

Not specified

Official deadline

January 7, 2028

446 days

Eligibility evidence

2 confirmed criteria

5 checks available

Application load

Moderate effort

01

Start here

Confirm eligibility

Check your fit in about 60 seconds.

Eligibility requirementsQuestion 1 of 5
About 60 seconds totalConfirmed criterion

Does your organization have the required nonprofit status?

What does this mean?

Eligible nonprofits are named in the source requirements.

Review supporting source ↗
Does your organization have the required nonprofit status?
Select an answer to continue

No signup · Answers stay in this browser session

This is an explainable self-assessment, not a win probability or legal determination. Hard eligibility conflicts are never averaged against softer program-fit signals. Always verify the official notice.

Optional Review source criteria and citations

Nonprofit status

Eligible nonprofits are named in the source requirements.

Review source ↗
confirmed

Geography

Nationwide availability is inferred from the catalog record; confirm the official notice.

Review source ↗
inferred

Organization size

No organization-size limit was captured.

Review source ↗
unclear

Program area

Education, Environment, Health, Income Security and Social Services, Human Services, Research

Review source ↗
inferred

Population served

No specific population was captured.

Review source ↗
unclear

Matching funds

No cost share is indicated.

Review source ↗
confirmed

Registrations

SAM.gov and Grants.gov registration may be required; confirm in the notice.

Review source ↗
inferred

Exclusions

Review the full notice for exclusions and prohibited uses.

Review source ↗
unclear
02

Grant-writer assessment

Understand the opportunity

Start with the practical interpretation. Open the complete source narrative when you need the underlying detail.

Plain-English explanation

Plain-English explanation

This opportunity supports dissemination and implementation research addressing barriers to the adoption, adaptation, integration, scale-up, and sustainability of evidence-based health interventions and related practices, programs, tools, treatments, guidelines, and policies. It also supports de-implementation research and studies advancing dissemination and implementation methods or measures. Every application must align with the mission of a participating NIH Institute or Center. Eligibility is broad, but the packet does not provide award amounts, expected award count, or formal review criteria.

Editorial analysis

What the funder is trying to accomplish

NIH intends to support studies that identify, develop, or test strategies for overcoming barriers across the implementation lifecycle of evidence-based interventions, practices, programs, tools, treatments, guidelines, and policies. The opportunity also covers de-implementation and the advancement of dissemination and implementation research methods and measures. Every application must fall within the mission of a participating Institute or Center.

Editorial analysis

Strong-fit project signals

The study directly addresses barriers to the adoption, adaptation, integration, scale-up, or sustainability of an evidence-based intervention, practice, program, tool, treatment, guideline, or policy. The study examines circumstances or strategies for stopping or reducing an ineffective, unproven, low-value, or harmful practice. The study advances dissemination and implementation research methods or measures. The proposed work falls within the mission of at least one participating NIH Institute or Center. The applicant belongs to a listed eligible category, including specified governmental, nonprofit, for-profit, higher education, tribal, federal, foreign, regional, territorial, faith-based, community-based, or other named institutional categories.

Editorial analysis

What reviewers may prioritize

Formal review criteria are not included in the packet. Based on the program purpose, scientific fit is likely to depend on whether the study addresses a specific dissemination, implementation, or de-implementation problem; identifies, develops, or tests an appropriate strategy or advances relevant methods or measures; and aligns with a participating Institute or Center's mission. These are inferred fit priorities rather than confirmed review criteria.

Source dossier Read the full official program description
Source-backed synopsis

What this grant funds

The purpose of this Funding Opportunity Announcement (FOA) is to support studies that will identify, develop, and/or test strategies for overcoming barriers to the adoption, adaptation, integration, scale-up, and sustainability of evidence-based interventions, practices, programs, tools, treatments, guidelines, and policies. Conversely, there is a benefit in understanding circumstances that create a need to stop or reduce (de-implement) the use of practices that are ineffective, unproven, low-value, or harmful. In addition, studies to advance dissemination and implementation research methods and measures are encouraged.All applications must be within the scope of the mission of one of the Institutes/Centers listed above.

Read the complete official description ↗
03

Decision economics

Size the opportunity

Use the source facts below to judge whether the likely return justifies the application effort.

Award range
Not specified
Total program funding
Not specified
Expected awards
Not specified
Geography
National
Cost share
Not indicated
Assistance listing
Not specified

Mission alignment

Compare your program with Education, Environment, Health.

Geographic fit

National

04

Working plan

Build the application

The generated milestones are planning aids. Only the official notice establishes required dates.

Requirements captured

Other requirements
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.
Submission system
Grants.gov
Attachments
https://grants.nih.gov/grants/guide/pa-files/PAR-25-143.html, PAR-25-143 Full Announcement Text
Contact
National Institutes of Health · grantsinfo@nih.gov · 301-402-2541

Official deadline

January 7, 2028

Moderate effort based on requirements currently captured.

  1. Confirm eligibility, registrations, partners, and internal approval.

  2. Finalize project design, outcomes, and supporting evidence.

  3. Draft the narrative and detailed budget.

  4. Complete compliance review and collect attachments.

  5. Submit early and preserve the confirmation receipt.

05Past behaviorCompare historical awardsHistorical patterns provide context, but do not predict or guarantee future funding decisions.
No licensed historical awards are currently linked to this opportunity.
06Audit trailVerify the evidenceSee where the facts came from, when they were checked, and what has materially changed.

Source record

What “source verified” means

The official record was successfully checked. Verification does not mean every eligibility or application field has been extracted. Read the methodology →

Verification
verified
Source
grants gov
Last checked
10/17/2026, 12:13:27 PM
Content updated
10/17/2026, 12:13:28 PM
Review
Automated normalization; not yet expert-reviewed
Open official source ↗

Material changes

  1. Updated eligibility, eligibility details.

  2. Updated eligibility, eligibility details.

  3. Updated eligibility, eligibility details.

  4. Updated eligibility, eligibility details.

  5. Updated eligibility, eligibility details.

  6. Updated eligibility, eligibility details.

  7. Updated eligibility, eligibility details.

  8. Updated eligibility, eligibility details.

  9. Updated eligibility, eligibility details.

  10. Updated eligibility, eligibility details.

  11. Updated eligibility, eligibility details.

  12. Updated eligibility, eligibility details.

Verify before applying. Official funder documents control. Derived analysis and preparation dates should not replace the notice.
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Quick answersFrequently asked questionsGet concise answers about Dissemination and Implementation Research in Health (R21 Clinical Trial Optional) Grant.
Is Dissemination and Implementation Research in Health (R21 Clinical Trial Optional) Grant currently open?

Yes, based on the latest source record. The deadline is January 7, 2028, with 446 days remaining. Because funders can amend or extend notices, confirm the date and submission instructions on the official application page. The source was last checked 10/17/2026.

How much funding does Dissemination and Implementation Research in Health (R21 Clinical Trial Optional) Grant provide?

Dissemination and Implementation Research in Health (R21 Clinical Trial Optional) Grant lists Not specified per award. The expected number of awards has not been captured, so the award range alone should not be treated as an estimate of competitiveness.

Who can apply to Dissemination and Implementation Research in Health (R21 Clinical Trial Optional) Grant?

Special district governments; Native American tribal governments (Federally recognized); City or township governments; Native American tribal organizations (other than Federally recognized tribal governments); Others (see text field entitled "Additional Information on Eligibility" for clarification);… Applicants should still complete the eligibility quiz and verify every condition in the official notice; a general fit does not override exclusions or registration requirements.

Does Dissemination and Implementation Research in Health (R21 Clinical Trial Optional) Grant require matching funds?

No cost-share requirement is indicated in the captured source facts. Applicants should still verify the official budget instructions in case an amendment, program track, or specific cost category carries additional conditions.

What should I prepare before applying to Dissemination and Implementation Research in Health (R21 Clinical Trial Optional) Grant?

Moderate effort is expected. The captured requirements include other requirements, submission system, attachments, contact. Start by confirming eligibility and registrations, then work backward from January 7, 2028 using the preparation plan above.