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Limited Competition: Small Grant Program for the NCATS Clinical and Translational Science Award (CTSA) Program (R03 Clinical Trial Optional)

This NIH/NCATS R03 opportunity targets CTSA Program KL2 scholars and CTSA-supported re-entry supplement recipients transitioning toward independence as academic translational scientists.…

Official application

Award

Up to $50,000

Deadline

October 19, 2026

1 day

Apply at official source Check your eligibility

No signup · Source checked 10/17/2026

Decision snapshot

Potential award

Up to $50,000

Official deadline

October 19, 2026

1 day

Eligibility evidence

2 confirmed criteria

5 checks available

Application load

Moderate effort

01

Start here

Confirm eligibility

Check your fit in about 60 seconds.

Eligibility requirementsQuestion 1 of 5
About 60 seconds totalConfirmed criterion

Does your organization have the required nonprofit status?

What does this mean?

Eligible nonprofits are named in the source requirements.

Review supporting source ↗
Does your organization have the required nonprofit status?
Select an answer to continue

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This is an explainable self-assessment, not a win probability or legal determination. Hard eligibility conflicts are never averaged against softer program-fit signals. Always verify the official notice.

Optional Review source criteria and citations

Nonprofit status

Eligible nonprofits are named in the source requirements.

Review source ↗
confirmed

Geography

Nationwide availability is inferred from the catalog record; confirm the official notice.

Review source ↗
inferred

Organization size

No organization-size limit was captured.

Review source ↗
unclear

Program area

Health, Human Services, Research

Review source ↗
inferred

Population served

No specific population was captured.

Review source ↗
unclear

Matching funds

No cost share is indicated.

Review source ↗
confirmed

Registrations

SAM.gov and Grants.gov registration may be required; confirm in the notice.

Review source ↗
inferred

Exclusions

Review the full notice for exclusions and prohibited uses.

Review source ↗
unclear
02

Grant-writer assessment

Understand the opportunity

Start with the practical interpretation. Open the complete source narrative when you need the underlying detail.

Plain-English explanation

Plain-English explanation

This NIH/NCATS R03 opportunity targets CTSA Program KL2 scholars and CTSA-supported re-entry supplement recipients transitioning toward independence as academic translational scientists. It supports short, limited-resource clinical and translational science projects intended to generate preliminary data for a subsequent R01 or equivalent application. The listed award ceiling is 50,000, with no cost sharing required. The listed deadline is October 19, 2026; applicants should confirm the applicable submission time, timezone, and current requirements in PAR-25-155.

Editorial analysis

What the funder is trying to accomplish

NCATS intends to enhance the research capability and independence trajectory of CTSA Program KL2 scholars and CTSA-supported re-entry supplement recipients. Supported work may include pilot or feasibility studies, secondary analysis, small self-contained projects, methodology development, or research-technology development. Projects may or may not include patient-oriented research but must be suitable for completion in a short period with limited resources and provide preliminary data for a subsequent R01 or equivalent application.

Editorial analysis

Strong-fit project signals

The project is centered on a CTSA Program KL2 scholar or a CTSA-supported re-entry supplement recipient and directly supports that researcher’s transition toward independence as an academic translational scientist. The proposed work is a pilot or feasibility study, secondary analysis of existing data, small self-contained research project, methodology-development project, or research-technology development effort. The work can be completed in a short period with limited resources and has a credible path to producing preliminary data for a later R01 or equivalent application. The proposed scope can operate within the listed 50,000 award ceiling without required cost sharing. The project may include patient-oriented research, but patient-oriented research is not required by the stated program description.

Editorial analysis

What reviewers may prioritize

Formal review criteria are not included in the supplied evidence. Based on the program purpose, likely considerations include alignment with the targeted CTSA researcher population, feasibility as a short and limited-resource project, relevance to clinical and translational science, and the ability to generate preliminary data for a subsequent R01 or equivalent application. These inferred priorities must be checked against PAR-25-155.

Source dossier Read the full official program description
Source-backed synopsis

What this grant funds

The purpose of this NOFO is to enhance the capability of NCATS CTSA Program KL2 scholars and recipients of re-entry supplements supported by the CTSA Program to conduct research as they complete the transition to fully independent academic translational scientists. These R03 grants will support different clinical and translational science research projects, including pilot and feasibility studies; secondary data analysis of existing data; small, self-contained research projects; development of research methodology; and development of new research technology. Research proposed in the R03 application may or may not include patient-oriented research. The R03 is, therefore, intended to support research projects that can be carried out in a short period of time with limited resources and that provide preliminary data to support submission of a subsequent R01, or equivalent, application.

Read the complete official description ↗
03

Decision economics

Size the opportunity

Use the source facts below to judge whether the likely return justifies the application effort.

Award range
Up to $50,000
Total program funding
Not specified
Expected awards
Not specified
Geography
National
Cost share
Not indicated
Assistance listing
Not specified

Mission alignment

Compare your program with Health, Human Services, Research.

Geographic fit

National

04

Working plan

Build the application

The generated milestones are planning aids. Only the official notice establishes required dates.

Requirements captured

Other requirements
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Submission system
Grants.gov
Attachments
https://grants.nih.gov/grants/guide/pa-files/PAR-25-155.html, PAR-25-155 Full Announcement Text
Contact
National Institutes of Health · grantsinfo@nih.gov · 301-402-2541

Official deadline

October 19, 2026

Moderate effort based on requirements currently captured.

  1. Confirm eligibility, registrations, partners, and internal approval.

05Past behaviorCompare historical awardsHistorical patterns provide context, but do not predict or guarantee future funding decisions.
No licensed historical awards are currently linked to this opportunity.
06Audit trailVerify the evidenceSee where the facts came from, when they were checked, and what has materially changed.

Source record

What “source verified” means

The official record was successfully checked. Verification does not mean every eligibility or application field has been extracted. Read the methodology →

Verification
verified
Source
grants gov
Last checked
10/17/2026, 12:13:27 PM
Content updated
10/17/2026, 12:13:28 PM
Review
Automated normalization; not yet expert-reviewed
Open official source ↗

Material changes

  1. Updated eligibility, eligibility details.

  2. Updated eligibility, eligibility details.

  3. Updated eligibility, eligibility details.

  4. Updated eligibility, eligibility details.

  5. Updated eligibility, eligibility details.

  6. Updated eligibility, eligibility details.

  7. Updated eligibility, eligibility details.

  8. Updated eligibility, eligibility details.

  9. Updated eligibility, eligibility details.

  10. Updated eligibility, eligibility details.

  11. Updated eligibility, eligibility details.

  12. Updated eligibility, eligibility details.

Verify before applying. Official funder documents control. Derived analysis and preparation dates should not replace the notice.
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Quick answersFrequently asked questionsGet concise answers about Limited Competition: Small Grant Program for the NCATS Clinical and Translational Science Award (CTSA) Program (R03 Clinical Trial Optional).
Is Limited Competition: Small Grant Program for the NCATS Clinical and Translational Science Award (CTSA) Program (R03 Clinical Trial Optional) currently open?

Yes, based on the latest source record. The deadline is October 19, 2026, with 1 day remaining. Because funders can amend or extend notices, confirm the date and submission instructions on the official application page. The source was last checked 10/17/2026.

How much funding does Limited Competition: Small Grant Program for the NCATS Clinical and Translational Science Award (CTSA) Program (R03 Clinical Trial Optional) provide?

Limited Competition: Small Grant Program for the NCATS Clinical and Translational Science Award (CTSA) Program (R03 Clinical Trial Optional) lists Up to $50,000 per award. The expected number of awards has not been captured, so the award range alone should not be treated as an estimate of competitiveness.

Who can apply to Limited Competition: Small Grant Program for the NCATS Clinical and Translational Science Award (CTSA) Program (R03 Clinical Trial Optional)?

Special district governments; Public and State controlled institutions of higher education; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Private institutions of higher education; Public housing authorities/Indian housing authorities;… Applicants should still complete the eligibility quiz and verify every condition in the official notice; a general fit does not override exclusions or registration requirements.

Does Limited Competition: Small Grant Program for the NCATS Clinical and Translational Science Award (CTSA) Program (R03 Clinical Trial Optional) require matching funds?

No cost-share requirement is indicated in the captured source facts. Applicants should still verify the official budget instructions in case an amendment, program track, or specific cost category carries additional conditions.

What should I prepare before applying to Limited Competition: Small Grant Program for the NCATS Clinical and Translational Science Award (CTSA) Program (R03 Clinical Trial Optional)?

Moderate effort is expected. The captured requirements include other requirements, submission system, attachments, contact. Start by confirming eligibility and registrations, then work backward from October 19, 2026 using the preparation plan above.